Publicaciones

Measles outbreaks, a public health focus

11 Apr

We have problems with measles. But the key question is not the acceptance of the vaccine, but access to it and problems with its effectiveness. Before thinking in mandatory policies, think in improving access and efectiveness. Measles outbreaks, a public health focus. Gérvas J. Madrid, Spain. April 2019. Download article here.

Medicine and its preventive excesses

18 Dec

With practical examples based on the real impact of medicalization in people lives and on the results from relevant and well designed studies, Juan Gérvas analyses the importance of certain screening programmes as breast cancer, thyroid cancer, the relevance of health check-ups and the impact of certain vaccines. He discusses the examples of Public Health [...]

Making use of the Food and Drug Administration briefing documents to reconsider the safety of the antipsychotic sertindole

2 Sep

Sertindole (Serdolect in the world, Zerdol in Germany) is an atypical antipsychotic agent, schizophrenia. Sertindole side effects include cardiac problems as prolongation of QT interval, arrhythmia and sudden deaths (higher than for other atypical antipsychotics). The FDA analysis of SCoP, made public in April 2009, estimated the hazard ratio for sudden cardiac death with sertindole [...]

Ovarian cancer screening: could you recommend it? No

15 Aug

In December 2015, The Lancet published the final results of The UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)  which “was designed to determine how many lives could be saved by screening for ovarian cancer”.  The UKCTOCS is another ovarian cancer screening that demonstrates that screening did not reduce  ovarian cancer specific mortality neither all-cause [...]

Ten commandments for the rational use of vaccines. November 2015

1 Nov

Vaccines are a treasure that is not defended and it is improved by simply repeating that mantra. The vaccine treasure requires good use and a continuous critical evaluation, in relation to developing and maintaining the vaccination schedules. Vaccination policies have been very poor in the recent decades, in the scientific, professional and political areas. This [...]

Social egg freezing (oocyte banking for anticipated gamete exhaustion). Ethical, practical and social problems

18 Sep

This text has two objectives: 1/to draw attention to an important issue in women’s health; and 2/to help train health professionals by providing evidence-based information about and criteria for what is called “social egg freezing.” Why don’t we extract eggs or ovarian tissue from women who are still young and then freeze and store them [...]

Overdiagnosis as an extreme form of length-time bias. Breast cancer screening as an example

14 Oct

Overdiagnosis is an error of prognosis. Overdiagnosis is not an error of diagnosis. Overdiagnosis is a “true positive” diagnosis. We cannot distinguish between overdiagnosis cancer and non-overdiagnosis cancer. In this presentation the focus is on the vision of overdiagnosis as extreme form of length-time bias, and the research lines which might help in the future [...]